Is there such a thing as too much optimism with Parkinson’s? I’ve asked myself that—but I’ve found that gratitude and hope aren’t just helpful, they’re essential. Optimism isn’t denial; it’s strength, perspective, and one of our most powerful tools.
A recent conversation with a couple of fellow physicians raised an important question:
Can too much optimism be a bad thing in people with Parkinson’s disease?
Am I potentially causing harm by encouraging people to work toward ignoring the negative and focusing all our energy on gratitude and what we can do?
Interestingly, an unrelated clinical trial caught my attention while I was reflecting on this. The authors noted that it is especially difficult to establish efficacy of treatments in people with Parkinson’s because we are more susceptible to the placebo effect.
I looked into it, and there is research that has shown that people with Parkinson’s disease are particularly susceptible to the placebo effect — more so than many other patient populations. When people with Parkinson’s expect a treatment to help, their brains can actually release dopamine — the very neurotransmitter that the disease depletes — leading to real, measurable improvements in symptoms.
In fact, studies using PET scans have demonstrated significant dopamine release simply from the expectation of benefit, even when no active treatment was given (de la Fuente-Fernández et al., Science, 2001).
I think this further supports my notion, that there is great power in thinking positively about our futures. That by believing we are capable of something great, it is possible that this in itself can lead to that “expectation of benefit” which can in turn result in dopamine release and symptom improvement.

This powerful mind-body connection reminds us: belief and hope are not just emotional crutches — they create real, biological change.
Some argue that focusing only on the positive might cause people to hide their struggles and live in denial. But many of us have found that optimism — grounded in gratitude — is one of our greatest tools for living well with Parkinson’s disease.
In fact, I would argue that this mindset is as powerful as exercise itself or medications.
While it’s important to acknowledge the challenges we face, leading with hope doesn’t mean ignoring reality. It means choosing to see opportunities even on hard days.
It’s recognizing that while the road ahead may have obstacles, we are not powerless.
Our attitude — our determination to move forward with faith, strength, and gratitude — remains firmly in our control.
One person with Parkinson’s said it beautifully: she likes to acknowledge the clouds but always look for the silver linings. I like this. I live this.
Yes, acceptance is a journey. And no, positivity is not about pretending every moment is easy. It’s about understanding that while struggle is real, so is our resilience.
Optimism builds resilience, reduces stress, strengthens our health, and helps us live fuller, richer lives.
Gratitude is what allows us to carry hope even when things are hard, and to celebrate victories — both large and small — along the way.
Choosing optimism doesn’t mean denying the storm; it means learning to dance in the rain.

In the end, we know the truth:
- Hope is not toxic
- Hope is power.
- Gratitude is the engine.
- And together, they light the path forward — no matter how tough the journey may be.
- Keep living.
- Keep fighting.
- Keep finding the beauty in today.
To close… my favorite quote:
“Gratitude makes optimism is sustainable.” — Michael J. Fox